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[41] Severe hepatic impairment constitutes a significant contraindication due to melatonins extensive hepatic metabolism
PubMed: 41090431 ClinicalTrials.gov
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The side effects of semaglutide include : Nausea Vomiting Diarrhea Abdominal pain Headache Fatigue Indigestion Dizziness Bloating Belching Flatulence Hypoglycemia (in people with type 2 diabetes) Stomach flu Gastroesophageal reflux disease (GERD) Cold-like symptoms The above side effects were reported by at least 5% of people in clinical trials
a figure that many patients on GLP-1 therapy fall short of, partly because the appetite suppression the medications produce makes hitting protein targets without conscious effort difficult. Clinical note Patients on GLP-1 therapy frequently report that protein-rich foods (particularly meat and eggs) become less palatable during treatment
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