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In the Retatrutide Phase 2 obesity trial, the weight-loss curve had not clearly flattened by week 48
Huwyler J, Wu D, Pardridge WM
Individual results depend on dose tolerated, genetics, diet quality, starting weight, and whether type 2 diabetes is present
An over-the-counter oral antihistamine like cetirizine (Zyrtec), loratadine (Claritin), or diphenhydramine (Benadryl) reduces histamine activity systemically and can relieve injection site itching within 30 to 60 minutes
Travel considerations require special planning
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