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Platelet activation relieves liver portal hypertension via the lymphatic system though the classical vascular endothelial growth factor receptor 3 signaling pathway

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doi: 10.1016/j.imlet.2009.10.006 90 HaasCSAminMARuthJHAllenBLAhmedSPakozdiAet al

This shifts clinical emphasis toward interventions with stronger evidence for preserving lean masssuch as adequate dietary protein and resistance trainingwhile complementary biological modulators like postbiotics may improve insulin sensitivity and inflammatory tone, thereby supporting metabolic resilience rather than directly increasing thermogenesis

More studies are needed in this area