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For example, in certain hereditary kidney diseases, gene editing of iPSCs to introduce pathogenic mutations enables the construction of kidney organoids exhibiting abnormal development and function, facilitating the clarification of genetic mechanisms and improving diagnostic accuracy ( In contrast to hPSC/iPSC-derived kidney organoids used to model developmental and non-neoplastic renal disorders, renal tumor organoids are tissue-derived platforms established directly from patient tumor samples
The aim of this study was to explore the role of MSC-derived sEVs (MSC-sEVs) and METs in treating mice with ALF
International society of sports nutrition position stand: Beta-Alanine
GLP-1 receptor activation inhibits glucagon secretion during normal and high blood sugar states, though critically not during hypoglycemia
Renal tissues from mice with CaOx crystal kidney injury and from negative control mice were collected for untargeted metabolomics