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"I try to explain that these are chronic medications, but I think everybody secretly feels, 'Yeah, but you know what, I'm different, and once I hit my weight goal, I'll be ok.' But the reality is, the brain is quite powerful." But this may not be the only explanation

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The biological plausibility is peer-reviewed and replicated

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Wegovy is approved for use in adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition