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Discontinue use if signs of irritation occur

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Following synthesis, the peptide undergoes purification using high-performance liquid chromatography (HPLC) to verify chemical purity and remove synthesis byproducts or truncated peptide fragments

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The reported outcome of this campaign was a candidate that retained agonist activity at amylin/calcitonin-family receptors while displaying a markedly extended pharmacokinetic profile in the authors' preclinical models, and reduced food intake in rodent models following administration