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The GLP-1RA liraglutide significantly reduces the eosinophilia and the production of type-2 cytokines species like IL-5 and IL-13 in the respiratory tract, while GLP-1R signaling downregulates innate allergic inflammation [135]

Conclusion GLP-1 therapies deliver substantial benefits, but they are not without risk

declares having received consulting honoraria from ANI Pharmaceuticals, Boehringer Ingelheim, Eli Lilly, Merck, Novo Nordisk and Oramed, and stock options from AltPep

Oscillating glucose (OsG), leading to glycemia fluctuation every 6 h for 24 h, is more deleterious to endothelial function and oxidative stress than stable glucose in normal and T2DM patients 6

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