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A more comprehensive understanding of POI pathogenesis, particularly the contribution of oxidative stress, could support the development of disease-modifying therapies, moving beyond symptomatic management

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The most alarming of these is its cancer risk

This conservative approach identifies any unusual sensitivity before significant exposure occurs

MALE INFERTILITY WHEREAS low levels of ROS (homologous to exercise or other necessary stress which makes us stronger) exert critical function in normal sperm physiology, such as fertilizing ability (acrosome reaction, hyperactivation, capacitation, and chemotaxis) and sperm motility

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