tirzepatide cardiovascular outcomes trial EFFICACY OF IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: AN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS OF 8 RANDOMIZED CLINICAL TRIALS Cardiorenal Outcomes With Tirzepatide Compared

This work was supported by NCCR AntiResist project funding (180541), SNF Sinergia (CRSII5_189952), Novartis Forschungsstiftung (FN24-0000000612), NIH Research Project (R01) (1R01AI173328-01) and the Desire and Niels Yde Foundation (543-23) to M.Z

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By employing summary-data based Mendelian randomization (SMR) and the Heterogeneity in Dependent Instruments (HEIDI) test, we identified single nucleotide polymorphisms (SNPs) whose effects on proliferative diabetic retinopathy (PDR) were mediated through levels of gene expression

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