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infiltration, histiocytes (monocytes)

In the late stages of PD, the key molecular pathogenic mechanisms include the misfolding and aggregation of -synuclein, mitochondrial dysfunction, impaired protein clearance (related to inefficient ubiquitin-proteasome and autophagy-lysosomal systems), neuroinflammation and oxidative stress (57)

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Among the tested oils, the leaf oil showed the highest yield with a predominance of eucalyptol (44.36%), -pinene (31.4%), limonene (5.06%), and -terpineol (3.62%)