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A mouse metabolises on a faster clock than a human, and a controlled diet in a cage is not a free-living human diet so even the week-numbers above should be read as the shape of a gradual response, not a promise that a human would see anything on the same calendar

Track progress through multiple metrics: scale weight (understanding water fluctuations affect this), body measurements at consistent points, progress photos in consistent lighting and posture, and subjective assessments of how clothing fits

5-Amino-1MQ selectively inhibits NNMT (IC50 = 1.2 M), an enzyme that consumes nicotinamide by methylating it

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Are the human side effects known