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Although the mouse model can mimic some of the pathological features of PCOS, its differences from human pathophysiology may affect the extrapolation of the results

Polymer solution contained 300 L PEGDA (d = 1.1 g/mL, Sigma), 600 L PBS, 5 L eosin Y

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(1998) characterized the compounds as Ang IV receptor agonists and some of them, e.g., 8 with the straight four-carbon chain of the Nle residue at position one, exhibited very high affinity to the binding site (IC50 values 30-fold higher affinity (Ki = 1.7 nM) than Ang IV and improved both selectivity and metabolic stability (Lukaszuk et al., 2008