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Following the aforementioned incidents, the development of lotiglipron was discontinued, and drug regulatory agencies in several countries classified GLP-1RAs as a potential risk factor for thyroid cancer, gallbladder, and biliary diseases
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10.1038/sj.ejcn.1602138 Verhoef P, van Vliet T, Olthof MR, Katan MB: A high-protein diet increases postprandial but not fasting plasma total homocysteine concentrations: a dietary controlled, crossover trial in healthy volunteers
50.5% achieved 15% or more loss