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The structure of B12 is based on a corrin ring which is similar to the porphyrin ring found in heme, chlorophyll, and cytochrome
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At a psychological level, a lack of vitamin B12 can lead to listlessness, depressive mood, difficulty concentrating, nervousness, and sleep disorders
More importantly, the observed increase in the bending rigidity modulus closely followed the measured changes in the area-per-lipid induced by cholesterol (Figure 2F)
As summarized below, literature on common classes of pharmaceutical compounds points to common observations of increased membrane fluidity, decreased molecular packing, and an overall softening of the membrane
Chapter 36: Megaloblastic anemias: disorders of impaired DNA synthesis by Ralph Carmel "George H
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