The best ways to prevent constipation are to stay highly hydrated, maintain a regular walking or exercise routine, and work with your provider on a slow titration schedule
Slowing gastric emptying, which prolongs the feeling of fullness and reduces appetite
doi: 10.1001/jama.2025.4735 147 HwangJHLaiteerapongNHuangESKimDD
TABLE 2 Summary of key epidemiological and observational studies on GLP-1 RAs and dementia risk
however, prolonged treatments may have further improve outcomes, which were not evaluated due to the logistics of performing these large studies with multiple different treatment arms
Overall prescribing trends The study found that 2,185,238 patients were prescribed a GLP-1 RA between January 2019 and December 2025, with 11,194,909 total prescriptions during this period