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These pathways are well-characterized in rodent models, though further confirmation in humans is needed

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Lipopolysaccharide causes an increase in intestinal tight junction permeability in vitro and in vivo by inducing enterocyte membrane expression and localization of TLR-4 and CD14

Gilliham M, Tyerman SD (2016) Linking metabolism to membrane signaling: the GABAmalate connection

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