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In this way, GLP-1 RAs exert cardiovascular and renal protective effects, improving nonalcoholic fatty liver disease through mechanisms including weight loss, blood glucose control, blood pressure reduction, lipid improvement, insulin resistance improvement, and inflammation and oxidative stress reduction [8]

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You J, Lee J, Hyun SH, Lee E

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Pharmacokinetic problems in peritoneal drug administration: tissue penetration and surface exposure

For Type 1 diabetes patients, GLP-1 drugs cannot replace insulin because these patients lack the beta cells needed for GLP-1-stimulated insulin secretion