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3 That study didnt report why 50% of diabetics on GLP-1 RAs discontinued them, but gastrointestinal (GI) adverse events were a suggested cause

Treatment significantly reduced levels of pro-inflammatory cytokines including interleukin-1 (IL-1) and tumor necrosis factor- (TNF-) while increasing anti-inflammatory interleukin-10 (IL-10) expression

When you increase a single-agonist like semaglutide, you are ramping one pathway

doi: 10.1111/cen.13454

It helps manage type 2 diabetes and aids in chronic weight management for adults with obesity