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The main difference is that AHK-Cu is a synthetic copper peptide

Some studies suggest better oral bioavailability compared to reduced glutathione, though research specifically examining liver outcomes is sparse

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The reason supervision matters is that some of these effects, particularly changes in heart rate and blood pressure, need monitoring rather than a wait-and-see approach

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None are currently FDA-approved for T1D, but off-label prescribing has been rising sharply and the clinical data is starting to catch up