While one study showed a vesicular staining pattern in polarized MDCK cells for endogenous TBC1D9B (although the specificity of the antibody remains unknown) 38 , in other studies, TBC1D9B was observed mainly in the cytoplasm 3 or in vesicles upon starvation and chloroquine treatment
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It is important to note that in addition to causing impaired detoxification symptoms which may mimic those related to thyroid disease, liver dysfunction can also affect the thyroid
DILI can manifest as various acute, subacute, or chronic liver injury types, with severity ranging from asymptomatic elevation of liver enzymes to fulminant liver failure or even death [7]
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