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This collaboration is Roche's largest investment in the past two years, following its $3.1 billion acquisition of Carmot, showing its strong commitment to the weight loss market
F.StubbsB.et al (2025)
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However, this does not prove that every symptom during weight loss is caused by toxicant mobilization, and current evidence has not established a unique GLP-1-related toxin release syndrome. Symptoms during GLP-1 treatment are more often explained by recognized medication effects, reduced food or fluid intake, dehydration, constipation, nutrient insufficiency, blood sugar changes, or gallbladder complications
