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Additionally, some drugs used for obesity and metabolic syndrome can affect TSH levels [76]
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In humans, intravenous administration of glucagon decreases plasma lipids, cholesterol and arachidonic acid through altered metabolic partitioning [56]
Rather than focusing solely on weight reduction, modern metabolic treatments aim to improve: insulin signaling fat distribution energy metabolism inflammation associated with excess adipose tissue This systems-level approach reflects the evolving understanding of obesity as a complex metabolic condition rather than simply a calorie imbalance
They work against each other
The gradual dose-escalation approach used with these medications serves to minimize gastrointestinal side effects while achieving therapeutic goals
