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Certain retained components of various cell death pathways such as Fas (CD95)/Fas ligand (FasL, CD95L) signaling, caspase-3, caspase-8, or RIPK1/RIPK3 (receptor-interacting serine/threonine-protein kinase 3)/MLKL (mixed lineage kinase domain like pseudokinase) axis can be considered a heritage of the erythroid lineage cells
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Once GSSG is formed, flavin adenine dinucleotide (FAD)-dependent enzyme glutathione reductase transfers electrons from NADPH, regenerating two molecules of GSH [121]
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As a result, more MT protein is synthesized
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