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Similar experiments with the ghrelin-receptor agonist GHRP-6 suggest that it may also provoke growth hormone peaks from basal values near 12 mU/L to around 60 mU/L, which corresponds to roughly a 30- to 50-fold increase over baseline and more than a threefold rise over usual physiological peaks of up to 20 mU/L

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Current evidence supports safe use for at least four years based on the SELECT trial