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Future trials should prioritize sufficient duration ( 1218 months), include high-risk subgroups (e.g., older adults, frail individuals, patients with rapid or marked weight loss, or chronic comorbidities such as chronic kidney disease), and integrate nutritional and resistance training interventions

Chin Med J

Beyond weight loss, early exploratory data suggest potential benefits including: Reductions in HbA1c (a marker of blood sugar control) in people with type 2 diabetes Improvements in lipid profiles (cholesterol and triglycerides) Reductions in liver fat, which may be relevant for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), though these findings are preliminary Possible cardiovascular benefits