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Overall, injections tend to produce the greatest average weight loss in clinical trials because they act on multiple hormone pathways
Participants with a BMI of 27 or higher were also included if they had at least one weight-related health condition, like high blood pressure, high cholesterol, or sleep apnea
sitagliptin 50 mg bid with metformin 500 mg bid, -1.6%
Body Works discusses it as a compounded option with a promising but still developing evidence base, and that framing is deliberate
State Medicaid programs face budget pressure, so obesity-drug coverage can change quickly
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