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Pathogenic variants in the WNK4 gene are associated with pseudohypoaldosteronism type IIB

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The beta chain of fibrinogen decreases 475%, reducing cardiovascular disease risk as elevated fibrinogen represents a powerful risk factor in cardiovascular health studies

In principle, the three signals are balanced so that appetite falls, energy output rises, and glucose control is preserved or improved

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doi: 10.1038/s41586-023-06651-y 98 KervevanJStaropoliISlamaDJeger-MadiotRDonnadieuFPlanasDet al