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After 28 days, even with proper refrigeration, both the preservative effectiveness and the peptide stability begin declining
Sixteen patients were contacted to review their knee pain symptom improvements 6 months to 1 year after receiving the injections
doi:10.1007/s10815-020-01836-0
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Moreover, injecting plain water into the bloodstream can be dangerous: without solutes, it is not isotonic to human blood and can cause red blood cells to burst (hemolysis)
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