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A recent study in JAMA of 4144 patients also found an elevated risk of gastroparesis and adverse gastrointestinal events with GLP-1 agonists
The tissue distribution of the amylin receptor complex is difficult to describe for a number of reasons: 1) the calcitonin receptor (the core unit) has two subtypes which interact with RAMPs, 2) RAMPs are associated with other receptors than the amylin receptor complex, and 3) there is a lack of selective pharmacological tools and antibodies to target specific amylin (RAMP/calcitonin) receptor complexes (26)
doi: 10.1016/j.coi.2010.03.007 65 PorichisFKaufmannDE
Lund, P
Sodium-glucose cotransporter-2 inhibition reduces cellular senescence in the diabetic kidney by promoting ketone body-induced nrf2 activation
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