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GT-activated prodrugs and potential nephrotoxicity Gamma-glutamyl transferase being the initial and limiting step in GT-activated prodrugs processing and because GT is highly expressed on the luminal surface of the proximal tubules in the kidney, potential nephrotoxicity could have been a limitation in the usage of this class of compound when administered systematically

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One commonly cited formulation lists 50 mg GHK-Cu, 10 mg KPV, 10 mg BPC-157, and 10 mg TB-500 per vial , for a total of 80 mg , with GHK-Cu accounting for 62.5% of the blend and each of the other three peptides contributing 12.5% by mass, according to Protide Healths KLOW peptide guide