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2013;27(3):303-313 Elam MB, Hunninghake DB, Davis KB, et al

Triple proline and glycine termini provide conformational flexibility enhancing solubility

[1] When combined, the cumulative effect on heart rate and blood pressure may be clinically significant, particularly in patients with pre-existing cardiovascular disease, uncontrolled hypertension, or arrhythmias

Never reuse needles, as dull needles cause more tissue trauma and discomfort

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Check for air bubbles, and if you see any in the syringe, gently tap it with your finger to bring them to the top, then push the plunger slightly to remove them