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They represent real setbacks for real people who worked hard to achieve their results
A phase 2, 16-week, open-label study in 18 subjects ranging from 6 to 40 years of age results in a mean BMI reduction of 18% in those younger than 18 years, and 6% for those 18 years or older, accompanied by significant reduction of hunger scores (127)
and possibly having direct effects in other organs (heart, brain, immune system)
Sometimes credited toward the program for new patients
Annals of Nutrition & Metabolism, 44(2), 7596
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