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The onset of pseudomembranous colitis symptoms may occur during or after the finalization of the antimicrobial treatment

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Pharmacological inhibition of the adenosine A2A receptor can also reverse myeloid-mediated immunosuppression and rescue CD8 T-cell function, sensitizing tumors to similar metastatic castration-resistant prostate cancer to atezolizumab and inducing a favorable ORR [182]

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Month 3+: Long-term use supports sustained metabolic improvement