In the epidermis of vitiligo lesions, a marked decrease in the expression of c-kit, the stem cell factor receptor, and the MITF transcription factor (microphthalmia-associated transcription factor) has been detected, along with a reduction in endothelin B receptor.40 A marked reduction in microRNA-211 expression has also been observed, associated with a lower oxygen consumption rate, aberrant mitochondrial complexes, alterations in lipid metabolism, and an increase in reactive oxygen species
Ngoi ra cn c vitamin C v nhiu cht chng oxy ha khc, gip kim sot sc t da, dng da sng u mu hn
Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillre R, Hannani D, et al
Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]
- combats heart muscle disease
Authors' perspective: What is the optimum intake of vitamin C in humans
