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A maintenance blueprint maps out concrete actions to maintain weight loss following drug therapy
A recent example is the SELECT trial finding that Ozempic (semaglutide) reduced cardiovascular events by 20% in overweight or obese adults with established heart disease and without diabetes
We are seeing a surge in patents for combination therapiesspecifically GLP-1s paired with myostatin or ActRII pathway modulators designed to protect muscle while deepening fat reduction
This systemic condition arises predominantly due to the interplay of two key components: (a) compromised insulin production by the pancreatic -cells, and (b) the failure of insulin-sensitive tissues to react to insulin
Maxillomandibular advancement has the best track record of any surgical option, with AHI reductions averaging more than 40 events per hour in the right candidates
Some patients may benefit from transitioning to alternative weight management medications if weight regain occurs, or from considering bariatric surgery if appropriate
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