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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

Skips the Digestive Tract: Delivered through nasal spray, peptides can be more readily available and act quicker than capsules as they bypass the digestive system

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Note: The review article states much LOWER quantities may be biologically active

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