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Further, direct stimulation of the GLP-1 receptor on cholangiocytes can lead to enhanced cellular proliferation and an elevated likelihood of cholestasis [47]

The target population was patients whose diagnosis of COVID-19 was confirmed based on Iranian ministry of health guidelines and hospitalized with mild-to-moderate disease

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Multiple sequence alignment analyses revealed that GSTO1-1 and GSTO2-2 contain a conserved catalytic cysteine residue and GSH binding sites, while other classes of GSTs have different amino acids in these positions, explaining why only GSTOs show DHAR activity 10,13