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Los factores que aumentan el riesgo de cogulos en pacientes con diabetes incluyen: Disfuncin endotelial: El revestimiento de los vasos sanguneos se daa por la hiperglucemia crnica Estado inflamatorio sistmico: Niveles elevados de marcadores inflamatorios como protena C reactiva Alteraciones de la coagulacin: Aumento de factores procoagulantes (fibringeno, factor VII) y disminucin de factores anticoagulantes Dislipidemia: Niveles anormales de colesterol y triglicridos que contribuyen a la aterosclerosis Obesidad: Especialmente la adiposidad abdominal, que se asocia con resistencia a la insulina e inflamacin Hipertensin arterial: Presente en aproximadamente el 70% de los adultos con diabetes tipo 2 Segn las guas de la ADA y el American College of Physicians (ACP), este riesgo aumentado incluye infarto de miocardio, accidente cerebrovascular, enfermedad arterial perifrica y, en menor medida, eventos trombticos venosos
Why GI side effects happen The area postrema sits outside the blood-brain barrier
In the SURMOUNT-5 trial (comparing tirzepatide to semaglutide at weight-loss doses), more people discontinued semaglutide due to side effects (5.6%) than tirzepatide (2.7%)
Why Medical Supervision Matters GLP-1-class medications require careful dosing, ongoing monitoring, and adjustments based on how your body responds
Published on Mar 23, 2026 | 1:44 PM Want to learn about a specific topic or condition
While nausea and gastrointestinal upset dominate the side effect profile, patients sometimes report unusual symptoms like coughraising questions about whether this respiratory complaint is truly linked to the medication or something else entirely
