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Kinins were analysed in plasma collected from 14 HAE-C1-INH and 8 HVs (prospective samples) and in plasma obtained from the Biorepository of the Hungarian Angioedema Center of Reference and Excellence from 16 HAE-C1-INH (3 were also included in prospective part of the sudy) and 4 HAE-nC1-INH participants (biobank samples)
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Due to the rapid metabolism of lidocaine HCl, any condition affecting liver function may alter its kinetics, which can double the half-life in patients with liver dysfunction
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