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reproductive endpoints typically appear in dedicated mechanistic studies or post-marketing investigations rather than primary efficacy trials

Opportunities Outside of Diabetes and Obesity Additional Indications for Exploration Additional Indications for Exploration As new companies look to enter the incretin mimetic space, and existing players seek to expand their portfolios, its increasingly important to look beyond diabetes and obesity

doi: 10.1007/978-3-642-14426-4_10 2 RoperSDChaudhariN

More serious but less common risks include pancreatitis, gallbladder disease, acute kidney injury (particularly in the setting of dehydration from gastrointestinal symptoms), and hypoglycemia when used in combination with insulin or sulfonylureas

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Effect of acupuncture and intervention types on weight loss: a systematic review and meta-analysis