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If GI side effects make it hard to take that medication consistently, we address it quickly
Whilst generally well-tolerated, it can cause gastrointestinal side effects (steatorrhoea, faecal urgency) that may be problematic in Crohn's disease
Retatrutide has the potential to expand Eli Lilly's addressable market across several dimensions: Patients with insufficient response to current drugs
Inadequate protein during a caloric deficit leads to muscle loss rather than fat loss, defeats the purpose of the protocol, and creates the metabolic slowdown that causes weight loss plateaus
8 , e2457349 (2025)
