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Why to Avoid: Risk of liver damage (hepatotoxicity) Gastric irritation and renal side effects Not recommended in children under 12 years Safer Alternatives: For fever / mild pain: Paracetamol For inflammation or body pain: Ibuprofen, Diclofenac, or Aceclofenac (as advised by physician) For arthritis or joint pain: Etoricoxib or other COX-2 inhibitors (doctors supervision essential) Lets promote rational drug use and ensure patient safety through responsible prescribing and dispensing

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This difference likely reflects the protective effect of GIP receptor co-activation

Pratter issued Case Management Order No