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The Mechanisms of Semaglutide Therapy in Heart Failure Patients trial will assess the impact of semaglutide on biomarkers, echocardiographic parameters, and functional outcomes in patients with HF [63]

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The most common adverse events included nausea, affecting 38.1% to 43.2% of treated patients compared to 10.7% with placebo, diarrhea in 33.1% to 34.7% versus 13.4% with placebo, and constipation in 21.8% to 25% compared to 8.7% with placebo

SGLT2 Inhibitors and GLP-1 Receptor Agonists in Diabetic Kidney Disease: Evolving Evidence and Clinical Application

It also helps the skin retain moisture