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New England Journal of Medicine, 387 (3), 205216

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Common side effects include: Gastrointestinal: Nausea, diarrhea, constipation, and abdominal pain (most common, usually transient) Decreased appetite: Expected and generally beneficial for weight management Injection site reactions: Mild redness or irritation at the injection site Rare but serious risks include: Pancreatitis (inflammation of the pancreas seek immediate medical attention for severe abdominal pain) Gallbladder disease Potential thyroid tumor risk (based on animal studies

According to the New England Journal of Medicine phase 2 clinical trial involving 338 adults, retatrutide showed significant weight loss, which was mainly dose-dependent

and is annually ranked among the top medical schools in the nation by U.S

YJZ: Conceptualization, Formal Analysis, Writingoriginal draft