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Description

After the presentations, the posters will be accessible within the "Presentations" section of NeuroBo's website at: About DA-1241 DA-1241 is a novel G-Protein-Coupled Receptor 119 (GPR119) agonist with development optionality as a standalone and/or combination therapy for both MASH and type 2 diabetes (T2D)

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[0044] The cleaving in step 7) is performed with TFA:PhSMe:PhOMe:EDT:H 2 O:TIS:PhOH=8090:05:03:05:05:02:05(V:V), with TFA:PhSMe:PhOH:EDT:H 2 O=85:5:3:5:2 being preferred

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NNMT catalyses the transfer of a methyl group from Sadenosylmethionine (SAM) to nicotinamide, producing 1methylnicotinamide and Sadenosylhomocysteine (SAH)

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