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When Metformin Remains a First-Line Choice Metformin remains the standard initial medication for type 2 diabetes because it is affordable, well-tolerated, has decades of safety data, and addresses insulin resistancethe root driver of many metabolic disorders
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10.1007/s10620-008-0332-9 130 SkorjanecS.KokotA.DrmicD.RadicB.SeverM.KlicekR.et al (2015)
Both showed consistent weight loss throughout the study period without any red flags that would suggest a hard stop date
Constipation left untreated can lead to complications such as a hemorrhoid, anal fissure, rectal bleeding, fecal impaction, and rectal prolapse
A growing body of research is revealing the profound, systemic effects of these drugs on a variety of health conditions
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