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Studies in tendon fibroblasts suggest BPC-157 can upregulate growth hormone receptors locally, making tissue more responsive to the body's own natural hormones

doi: 10.1186/s12951-025-03708-0

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GHK-Cu modulates expression of over 4,000 genes through copper-dependent pathways, including collagen synthesis, metalloproteinase regulation, and antioxidant defense

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IR -subunit heterozygous mice 135 and complete disruption of IRS2 in mice 136 impaired the LTP of synaptic transmission in the hippocampus