Mar 2012;3(2):158-165
Wegovy and mental health safety In 2023, reports of suicidal thoughts in people taking GLP-1 receptor agonists (a class of weight loss medications that mimic gut hormones) prompted safety reviews by the European Medicines Agency, the UKs MHRA, and the US Food and Drug Administration
What happens during traditional dieting: Resting metabolic rate drops by 15-25% beyond whats expected from weight loss Lean muscle mass decreases significantly Hormones that regulate hunger and satiety become dysregulated The body becomes incredibly efficient at storing fat Energy levels plummet and motivation decreases Energy restriction is accompanied by changes in circulating hormones, mitochondrial efficiency, and energy expenditure that serve to minimize the energy deficit, attenuate weight loss, and promote weight regain
Picture turning down a smoke alarm without putting out the fire
Do not discontinue Wegovy without medical advice, as your clinician may suggest dose adjustments, additional investigations, or alternative management strategies
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