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Greater molecular complexity tends to make a drug harder to stabilize, harder to manufacture consistently, and harder to get through the digestive system intactall of which matter when researchers are trying to move a medication from injectable form to pill form
doi: 10.21037/atm.2020.02.172 98 LiuWJShenTTChenRHWuHLWangYJDengJKet al
Increased heart rate: A modest, dose-dependent increase was observed in trials, peaking around week 24 before declining
The off-label status may impact some patient coverage and claim reimbursement determinations even though the drug is approved by FDA for at least one other (label) use
Dispensing of glucagon-like peptide-1 receptor agonists to adolescents and young adults, 20202023
Mahdi M, Almehman B, Nassan S, Binyahib S
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