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Current research limitations include the absence of large-scale randomized clinical trials in humans, an still partial understanding of the precise molecular mechanisms, and a lack of detailed pharmacokinetic data in humans

Viral supernatants were harvested twice at 48- and 72-hrs post-transfection

SAM-e has been approved and marketed as a treatment for psychiatric disorders in Europe for over 25 years, but, in the US, it is sold as an over-the-counter supplement [ R ]